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European Journal of Prosthodontics and Restorative Dentistry  —  Vol. 34, Issue 1 (January 2026) ← Back to issue
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Clinical Evaluation Of Local Anaesthetic Efficacy In Patients With Oral Mucosal Disorders Undergoing Prosthodontic And Restorative Treatment

DOI: 10.1922/EJPRD_2865Kharat20
Keywords

Local anaesthesia, Oral mucosal disorders, Prosthodontic treatment, Restorative dentistry, Patient-reported outcomes

Authors

Dr. Avina Kharat1*
1*
MD Pharmacology, Senior Resident,
ESIC Medical College and Hospital
Indore,
ORCID
ID
https://orcid.org/0009-0000-5502960X, avinak30@gmail.com
Swetha Makkena2
2
Bachelor
of
Dental
Surgery,
Department of Oral Medicine and
Radiology, SRM Dental College,
Ramapuram, Chennai, Tamil Nadu,
600089, INDIA, ORCID ID: 00090006-4400-2819,
makkenaswetha76@gmail.com
Dr.Abarna Jawahar3
3
Senior Lecturer, Department of Oral
Medicine and Radiology, Sree Balaji
Dental College & Hospital Bharath
Institute of Higher Education and
Research (BIHER) ORCID ID - 00000001-7937-3923,
drabarnajawahar@gmail.com

Dr. Bharathi SH4
4
Professor and Head, Periodontology
and Implantology, RGUHS, GDCRI
ORCID ID: 0009-0000-0175-5761,
bharathish70@gmail.com

Dr. K Sadananda5
5
Assistant Professor, Department of
Periodontics
and
Implantology,
RGUHS, GDCRI. ORCID ID: 00090006-1400-3765,
sadaperio@gmail.com

Dr Mohammed Ismail B6
6
Professor,
Department
of
Periodontology And Implantology,
RGUHS, GDCRI. ORCID ID: 00090001-6362-0902,
ismail2220333@gmail.com

Received: 02.01.2026
Accepted: 27.01.2026

European Journal of Prosthodontics and Restorative Dentistry (2026) 34 (1) , 08–15

Clinical Evaluation Of Local
Anaesthetic Efficacy In
Patients With Oral Mucosal
Disorders Undergoing
Prosthodontic And
Restorative Treatment

Abstract

Successful oral mucosal disorders that can change the perception of pain and tissue sensitivity necessitate the use of effective local anaesthesia to administer successful prosthodontic and restorative dental care. The study aimed to determine the perceived effectiveness of local anaesthetic methods in patients with oral mucosal disorders during prosthodontic and restorative dental treatment in a randomised clinical trial incorporating patient-reported and practitioner-reported outcome measures. A cross-sectional observational study was carried out using a questionnaire based on observational research in 50 adult patients who received oral mucosal disorder treatment of some kind, either through prosthodontic or restorative treatment, under the influence of local anaesthesia, and their treating prosthodontists or restorative dentists. Demographic and clinical data, patient-reported outcome data regarding pain relief, onset and duration of anaesthesia, patient comfort during the procedures, and practitioner-reported outcome data regarding anaesthetic adequacy and clinical manageability were collected by using a structured, validated questionnaire. The responses were measured with a five-point Likert scale. Inferential analysis was conducted using non-parametric tests, such as MannWhitney U and Spearman's rank correlation tests (descriptive statistics were applied). The local anaesthetic methods were reported to have a high degree of perceived effectiveness with positive ratings to pain control, onset, duration and overall procedure comfort. Patients whose oral mucosa is in an active state complained of more sensitivity and intra-procedural discomfort and were more prone to supplemental anaesthetic administration than those with controlled or remission conditions (p < 0.05). An intermediate positive association was evident between patient-reported pain and practitioner-reported anaesthetic supplementation (0.52, 0.01). In cases of oral mucosal disorders, the standard local anaesthetic practices are still effective in clinical practice in prosthodontic and restorative treatment of patients. Personalized anaesthetic preparation and adaptive methodology of technique are beneficial in improving patient comfort and procedural efficiency in normal clinical practice. 1. Introduction Local anaesthesia has been a pillar in the contemporary dental practice, where it is used to carry out the procedures of prosthodontics and restorative dentistry with painlessness and also provide comfort to the patient and efficiency in carrying out the procedure. Successful delivery of local anaesthetic has a direct effect on the acceptance of treatment, clinical accuracy and patient satisfaction. Although the field of anaesthetic pharmacology and technique has been maintaining development, the variability in anaesthetic response remains a problem for clinicians, especially in patients who come with altered oral tissue conditions. Thorough analyses have highlighted that the efficacy of anaesthesia is determined by elements that can include tissue health, neural anatomy, ••••••••••••••••••••••••••••••••

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Article Information
Pages
8 – 15
Cover Date
January 2026
Volume
34
Issue
1
Electronic ISSN
2396-889