Radiological features, Clinical presentation, hemiparesis, quadriparesis, bladder dysfunction
AuthorsAbstractBackground: Pontine stroke is an uncommon but potentially life-threatening subtype of posterior circulation stroke due to the critical neuroanatomical functions of the pons. Despite its clinical significance, data from northeastern India are scarce. This study aimed to describe the clinical profile, radiological features, management, and short-term outcomes of patients with pontine stroke treated at a tertiary care hospital in Tripura. Methods: A hospital-based case series was conducted in the Department of Medicine, Agartala Government Medical College and GBP Hospital, Tripura, from February to July 2023. Ten consecutive patients with radiologically confirmed pontine stroke were enrolled. Demographic characteristics, vascular risk factors, clinical presentation, neuroimaging findings, treatment, complications, and in-hospital outcomes were recorded using a structured data collection form. Results: Among 136 admitted stroke patients, 10 (7.35%) had pontine stroke, of whom, 91.6% were identified as pontine hemorrhages. The mean age was 63.3 years, with a male predominance. Hypertension was the most common risk factor (50%), followed by diabetes mellitus, dyslipidemia, smoking, and family history of stroke. Clinical manifestations ranged from crossed hemiparesis, quadriparesis, vertigo, dysarthria, and impaired consciousness to rare presentations such as one-and-ahalf syndrome and bladder dysfunction secondary to pontine infarction. Patients with massive pontine hemorrhage had poor outcomes, accounting for an overall mortality of 30%, whereas those with small hemorrhages recovered well with conservative management. Conclusions: Pontine stroke exhibits diverse clinical manifestations and variable outcomes. Early neuroimaging, prompt recognition, aggressive blood pressure control, and multidisciplinary supportive care are essential to improve prognosis. Larger multicentric studies with long-term follow-up are warranted to validate these findings and identify prognostic factors.
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