Surgical site infection; exploratory laparotomy; emergency surgery; elective surgery; antibiotic resistance; postoperative complications.
AuthorsAbstractBackground: Surgical site infections are among the most common healthcare-associated infections worldwide and disproportionately affect patients undergoing emergency laparotomy. Objective: To evaluate and compare the occurrence, microbiological profile and outcomes of SSIs following emergency versus elective exploratory laparotomy. Methods: This prospective observational study was conducted in the Department of General Surgery, Dhiraj General Hospital, India, between November 2023 and March 2025. 102 patients undergoing exploratory laparotomy were enrolled (elective n = 61, 59.8%; emergency n = 41, 40.2%) and followed for 30 postoperative days. SSIs were classified using CDC criteria (1,2). Categorical variables were compared by chi-square test, continuous variables by independent-sample t-test. Results: Mean age was comparable (45.84 ± 15.07 vs 48.00 ± 18.59 years; p = 0.519). Males were more frequent in emergency cases (80.5% vs 57.4%; p = 0.015). Diagnoses differed significantly (p = 0.002), intestinal perforation (26.8%) and gastrointestinal perforation (17.1%) predominating in emergency cases. Alcohol use was significantly more common in emergency patients (19.5% vs 4.9%; p = 0.015). The overall SSI rate was 28.4%, markedly higher in the emergency group (41.5%) than the elective group (19.7%; p = 0.017). Escherichia coli was the most frequently isolated organism in both groups (33.3% vs 47.1%); the microbiological distribution (p = 0.824) and antibiotic responsiveness (p = 0.367) did not differ significantly between groups. Conclusion: Emergency exploratory laparotomy is associated with markedly elevated SSI risk compared with elective procedures. Microbial profiles and antibiotic responsiveness are comparable, indicating prevention - not antimicrobial modification — is the principal modifiable lever.
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